Bio-regeneration: laying the foundation for multi-level combination

REPORT summary

Patient

52-year-old female, Fitzpatrick II, presenting with aging-related changes involving both superficial and deep dermis.

Results

Treating both superficial and deep dermal layers produced superior improvement in texture, hydration, and overall rejuvenation. The dual-depth stimulation likely enhanced fibroblast activation at multiple levels, confirming the benefit of multilevel anti-aging strategies.

Treatments

A multilevel “sandwich technique” using Neauvia Hydro Deluxe 2 ml per side across two sessions one month apart. One side received 1 ml deep intradermal injection (30G, 13 mm) + 1 ml superficial microneedling (0.2 mm).

The other side received 2 ml injected deeply. A split-face design allowed clinical and instrumental comparison.

Dr Maurizio Cavallini
Plastic Surgeon
Italy

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